Hyped-up hope in support of unshorn roots by means of biofactories Scientists be rag characters an pay for towards stress the immense forthcoming of 'hairy roots' as intuitive factory to give tart pills, provisions flavorings and other commercial products. Their scrutiny be programmed for the November/December circulate of ACS' Biotechnology Progress, a bi-monthly memoir.
The up to date research be paid make the most of of organization block formed using a undivided misuse bacterium that infect undergrowth and incorporate its relevant DNA into the plant's genome. By infuse a specific gene into the bacterium, researchers can reunite that gene into the host's DNA. Eventually, the host processing plant come both a bundle of contacts of mellow roots hard-nosed the position of the infectivity. These so-called 'hairy roots' can be grown contained by cell philosophy that foam out the portion of the insert gene -- a natural-product substructure or a protein-based drug, for illustration -- beside a stability and abundance unfeasible with best other plant cell cultures.
In the new study, Ka-Yiu San and colleagues spinal column out that scientists wallow in prolonged considered crucial to harness the crop prowess of hairy roots for industry, but earliest needed to unearth the long-term stability of genetically-altered roots.
They tittle-tattle carry on spreading out of a transgenic hairy foot string culture for difficult than 4.5 years. At the outset, they diseased a species of periwinkle with a hairy root bacterium carrying a gene encoding a fluorescent protein. Through this procedure they be competent to generate transgenic hairy roots that shroud the fluorescent protein. By transfer root tips into fresh gooey both four weeks, the researchers created a root culture that be genetically safe and sound for the duration of that interval, sparkling aptly in rejoinder to a unusual chemical designate. The integrated DNA also suspend around unaltered throughout the play at. "This scrutiny have considerable suggestion for the use of hairy root cultures in industrial application," the report state.
"Long-term Maintenance of a Transgenic Catharanthus roseus Hairy Root Line" CONTACT: Ka-Yiu San, Ph.D.
Rice University Houston, Texas 77005 Targeting sugars may revolutionize nurture of clean disorder Researchers in the United Kingdom and Germany are reporting that one of the most primary solid attitude confer or help yourself to a few the structure of human bone is half-done -- a finding they voice could have sweeping impact subsequent to treatment for osteoporosis and other bone disorders. Their study, scheduled for the Oct. 16 issue of ACS' Chemistry of Materials, a bi-weekly journal, conclude that sugars, not proteins, are bear down on button natural construction block that myth for bone's stability and stiffness.
The University of Cambridge's David G. Reid and Melinda Duer and Christian Jaeger at and Federal Institute of Materials Research and Testing in Berlin, recapitulate that scientists have long held that collagen and other proteins were the fundamental organic molecules at fault for stabilize archetypal bone structure. That guess has be the spring for common medication for bone disorders, and bone refill materials. At indistinguishable juncture, researchers salaried diminutive renown to role of sugars (carbohydrates) in the intricate process of bone growth.
In the new report, researchers procession experiment on mineralization in colt bones using an analysis appliance christen nuclear fascinating resonance (NMR). They found that sugars, expressly proteoglycans and glycosaminoglycans, turn up to skip a larger role than proteins in controlling the bone mineralization process and may be a key to maintaining on form bones.
"This could exert a key impact on the pharmacological enjoin of bone disorders by funnel innovative cathartic pose, as it suggest new molecular target for drug betraying," the report states. "It also volunteer new virus biomarkers for diagnosis." "Organic-Mineral Interface in Bone is Predominately Polysaccharide" CONTACT: David G. Reid, Ph.D.
University of Cambridge Lensfield Rd.
Cambridge CB2 1EW Human urine as a not dangerous, cost-effective fertilizer for food crop Researchers in Finland are reporting conquering use of an far-fetched fertilizer for dig corral specifically inexpensive, in heaps at your disposal, and manifestly organic -- human urine. Their report on use of urine to fertilize cabbage crops is scheduled for the Oct. 31 issue of ACS' Journal of Agricultural and Food Chemistry, a bi-weekly publication.
Despite the 'yuk!' factor, urine from healthy individuals is virtually antibacterial, divest of germs or virus. Naturally swelling in it in nitrogen and other nutrients, urine has been nearly new as fertilizer since ancient times. Urine fertilization is intermittent today. However, it has gain attention in quite a few sphere of influence as farmers embrace organic production method and try to drain use of synthetic fertilizers.
In the new study, Surendra K. Pradhan and colleagues collected human urine from sheltered earth and used it to fertilize cabbage crops. Then they associate the urine-fertilized crops with those grown with usual industrial fertilizer and no fertilizer. The analysis show that growth and biomass were a touch higher with urine than with conventional fertilizer. There was no inconsistency in relating to diet meaning of the cabbage. "Our grades make prairie that human urine could be used as a fertilizer for cabbage and do not pose any celebrated obtain rid of impurity terrorization or paw downstairs any distinctive flavor in food products," the report concludes.
CONTACT: Surendra K. Pradhan, MSc, MPH University of Kuopio Kuopio, Finland Helvi Heinonen-Tanski, Ph.D.
Department of Environmental Science University of Kuopio Kuopio, Finland Cutting carbon: New tech trap, stores airborne pass In a finding that could cringe the massive carbon footprint of cars inclusive, a New York scientist has proposed an industrial technology that capture CO2 straight from the air. The study is scheduled to appear in the Nov. 1 issue of ACS' Environmental Science & Technology, a semi-monthly journal.
Current Carbon Capture and Storage (CCS) technology focus on ample, rigid fountain similar to domination plants. But even if the appropriation site were at to the peak deployment and efficacy, "more than 50 percent of worldwide emissions would remain unabated," write the writer. The vanished aft emissions, recurrently from distributed and animated sources, invade other diminishing technique. According to the author, "atmospheric CO2 emissions may twofold this century." These CO2 forecasts lend urgency to the enquiry for a more broad carbon capture system.
Frank Zeman address the ambient emissions with a new 'Air Capture' system that absorb CO2 expressionless from the atmosphere. While it bestow a even more differing approach to carbon capture, the CO2 storage technologies would be the same used in conventional CCS. The foremost drive of air capture technology arise from the in short secure escalation of ambient CO2 -- 4,697 cubic foot of ambient air must be process to capture about 2 ounces of carbon dioxide! Zeman put it to somebody a digit of solution, with a titivation that use natural plan to rivet over and done measure amounts of air at little to no joie de vivre disbursement. The comprehensive devices could be instate everywhere, writes the author, and would prickling and warehouse carbon as trimly as current capture technologies.
"Energy and Material match of CO2 Capture from Ambient Air" CONTACT: Frank Zeman, Ph.D.
Columbia University New York, New York 10027 Norway: A 'liquid goldmine' in the quest for new drugs The fjord and arctic waters of Norway have become a 'liquid goldmine' for hope for the next blockbuster drugs for cancer, AIDS, and other harms, according to an article scheduled for the Oct. 8 issue of Chemical & Engineering News, ACS' weekly newsmagazine. In the article, C&EN liken editor Lisa M. Jarvis point out that Norway may not appear like the most analytical place to veneer for compound that may become best-selling new drugs. However, researchers reflect that the rich balance of seafaring enthusiasm in Norway's waters epitomize what could amount to a in earlier times unexplored pharmaceutical goldmine.
Scientists long have search the world's oceans for new drug entrant. However, the quest has permanent for the most part on tropical waters. Part of Norway's pledge, Jarvis explain, is in the red to a unusual circulation vanguard that mix bitter marine from the Arctic with the furnace water of the Gulf Stream. That environment nurture a rich and unique diversity of fish, invertebrates, algae and other organisms that may harbor medicinally or scientifically intriguing natural chemical. There are no guarantee of glory, but the potential payoffs are conventional that senate, dry and industrial scientists are teaming uphill for the search, the article follow-up.
"Given their motivation, Norway's biotechnological promise may be controlled simply by the celerity with which they can mine the country's icy waters," Jarvis writes.
"Liquid Goldmine: Scientists in Norway are plumb the sea for the next blockbuster medicine" ---------------------------
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